Dr. Buckley was recently awarded an R01 from the NINDS to study the role of p38 MAPK signaling in neurons after repetitive mild traumatic brain injury. This multi-disciplenary work will be performed with co-PI Dr. Levi Wood (Georgia Tech, Mechanical Engineering). It is well known that repetitive mild traumatic brain injuries (rmTBIs) can lead to long-term cognitive changes, neurodegeneration, and dementia. However, the mechanisms responsible for the long-term effects of repetitive mTBI are poorly understood and effective therapeutic strategies are lacking. This proposal will use a physiologically relevant mouse model of repetitive mTBI to determine if stress response in neurons is responsible for triggering neuroinflammation, loss of cognitive function, and reduction in brain blood flow.

We currently have two Research Technician openings, one to help manage our preclinical studies, and one to help with clinical studies. See the Join the Team tab for more information on job responsibilities, qualifications, and how to apply.

In our latest publication, lead author Eashani Sathialingam developed and validated a novel tissue-simulating phantom for DCS that contains hundreds of embedded micron-sized channels. She then uses this platform to investigate the influence of hematocrit on the DCS-measured blood flow index. Check more details here: https://www.osapublishing.org/boe/abstract.cfm?uri=boe-11-8-4786