Check out our latest paper in Neurophotonics! Lead author Hongting Zhao explores the influence on the choice of source-detector separation on the accuracy of brain blood flow measured with DCS. It is well known that perfusion in the scalp and skull can significantly influence Diffuse Correlation Spectroscopy (DCS) estimations of brain blood flow. Analytical approaches that model the head as a layered structure aim to minimize these influences. Here we demonstrate that the choice of source-detector separations when using these models is imperative to minimize errors in the estimation of brain blood flow.

Check out our latest paper in Frontiers of Neurology. In this work, we used NIRS and DCS to monitor the effects of blood transfusion on the brain in children with sickle cell disease. The results demonstrate how diffuse optical spectroscopies may be a promising bedside tool for real-time monitoring and for goal-directed therapy aimed at reducing stroke risk in sickle cell disease. Congrats to lead authors Rowan Brothers and Paul Lee!